Tadalafil drug is a selective inhibitor of phosphodiesterase type 5 (PDE 5) specific to cyclic guanosine monophosphate (cGMP). When sexual stimulation causes local release of nitric oxide, inhibition of PDE 5 by Tadalafil leads to increase of cGMP levels in the erectile body of penis. There is a relaxation of arterial smooth muscle and the blood supply to tissues in the penis causing an erection. Tadalafil has no effect when sexual stimulation is missing. Cheap Tadalafil improves erection and lets you to complete sexual intercourse. The drug acts during 36 hours. If there is sexual arousal, the effect appears after 16 minutes after the medication was.
Dosage and direction
Tadalafil is available in 10 mg, 20 mg and tadalafil sublingual tablets. The usual recommendation is Tadalafil 20mg that must be taken prior to the sexual activity. The dose may be decreased to 10 mg or 5 mg, based on individual efficacy and tolerability. The maximum recommended dosing frequency is once per day in most patients. Buy tadalafil at cheap cost in our online pharmacy Global Generic Pharmacy.